Material available
A variety of biological material is available for the research community. In order to access samples, your project must be approved for access. For more information on you can obtain approval click here.
The project collects paired samples of tumour and normal tissue from thyroid patients undergoing operations for thyroid cancer or adenoma in the Institute of Enodcrinology and Metabolism in Kiev, Ukraine and the Medical Radiological Research Centre in Obninsk, Russia. Tissue is collected to an approved standard operating procedure (SOP) and is snap frozen, and the presence or absence of tumour is verified by frozen section. A representative paraffin block is also obtained for each case. Where appropriate, we also collect fresh and paraffin tissue from loco-regional metastases. Currently we do not issue tissue, but provide extracted nucleic acid, paraffin sections and sections from tissue microarrays from this material.
Cases which have been reviewed, broken down by tumour type (more detailed information can be provided on request from the CTB Secretariat); the number of cases for which frozen material is available given in brackets.
| |
Ukraine |
Russia |
Total |
| Papillary Carcinoma |
678 |
(566) |
363 |
(295) |
1041 |
(861) |
| Follicular Carcinoma |
51 |
(41) |
16 |
(15) |
67 |
(56) |
| Medullary Carcinoma |
19 |
(16) |
15 |
(8) |
34 |
(24) |
| Other cancers |
30 |
(28) |
19 |
(14) |
49 |
(42) |
| Follicular Adenoma |
246 |
(193) |
157 |
(137) |
403 |
(330) |
| Other Benign Follicular Tumours |
54 |
(45) |
46 |
(35) |
100 |
(80) |
| Miscellaneous Tumours |
29 |
(18) |
55 |
(52) |
84 |
(70) |
| Total |
1107 |
(907) |
671 |
(556) |
1778 |
(1463) |
Table updated 02.10.2006
The majority of the cases (80%) are from the contaminated
areas of Ukraine and Russia. 193 cases are from patients who
were born after 1 st December 1986 and who were therefore
not exposed to radioiodine in fallout either in utero or as
children.
more information:
Aliquots of nucleic acid
Paraffin sections
Tissue Micro Arrays
|
