Aliquots of nucleic
acid
Aliquots of nucleic acidRNA and DNA is extracted
from histologically verified frozen specimens in Ukraine and
Russia. Extraction is carried out to internationally agreed
SOPs. The Institutes in Ukraine and Russia and the Coordinating
Centre carry our detailed quality assurance using Agilent
Bioanalysers.
Cases on which aliquots of nucleic acid
are available at the current time. Please contact the CTB
Secretariat for more details.
Table updated 31.01.2008
| Path Panel |
No of |
Tumour |
Normal |
Metastasis |
| Diagnosis |
cases |
DNA |
RNA |
DNA |
RNA |
DNA |
RNA |
| Cancer |
321 |
302 |
299 |
291 |
290 |
37 |
51 |
| (of these PTC) |
(273) |
(260) |
(256) |
(254) |
(251) |
(39) |
(50) |
| Benign |
115 |
105 |
112 |
81 |
84 |
|
|
| (of these FA) |
(73) |
(65) |
(72) |
(46) |
(50) |
|
|
| Other |
7 |
5 |
7 |
7 |
7 |
|
|
| Totals |
443 |
414 |
418 |
379 |
381 |
37 |
51 |
Aliquots of DNA from blood are also available, in
the majority of cases these can be paired with samples of
RNA and DNA from tissue from the same patient. DNA is extracted
using Qiagen kits.
Serum
Aliquots of serum are also available. These are prepared
to an agreed SOP (click here for details).
There is no fee payable for provision of
aliquots of nucleic acid or serum, but investigators will
be asked to cover the costs of transport of the samples.
Paraffin sections
Sections are available from routine formalin fixed,
paraffin embedded tissue and from tissue microarrays (click
here for information on tissue microarrays).
The CTB is required to recover the costs of provision of this
material.
Costs for paraffin sections from individual paraffin blocks
are as follows:
20 US$ for the first section from each block, 3US$ for each
subsequent section
|
